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M-CEDRA-BR-00063 - Agosto
2023 | Material destinado a todos os públicos
a. Melhora na hidratação cutânea observada 30min após a aplicação de
b. Ação referente ao cédrat. Essa ação se refere às atividades evidenciadas na
literatura científica envolvendo estudos in vivo e in vitro realizados com o extrato
de Citrus medica L. 6-11
1. Rotulagem de cedraflon®
2. Pesquisa realizada pelo Instituto IBOPE - JOB 1036/16, na cidade do Rio de
Janeiro com 50 mulheres. Outubro/2016. Código para acessar no veeva: REF13738
3. INSTITUT D’EXPERTISE CLINIQUE (IEC). Clinical study for the evaluation of
the moisturizing effect of a cosmetic investigational product, after a single
cutaneous application, in the adult subject. N° 160097RD – Version 1, of
19/04/2016, França
4. BROMMA, B et al. Eects of menthol and cold on histamine-induced itch and skin
reactions in man. Neuros-cience Letters, V. 187, N. 3, P. 157-160. 1995.
5. Biosaccharide-gum-1. https://www. Acessado em: maio 2021
6. MENICHINI, Federica et al. Phytochemical profile, antioxidant, anti-inflammatory
and hypoglycemic potential of hydroalcoholic extracts from Citrus medica L. cv
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7. MENICHINI, Francesco et al. Citrus medica L. cv Diamante (Rutaceae) peel
extract improves glycaemic status of Zucker diabetic fatty (ZDF) rats and protects
against oxidative stress. Journal of Enzyme Inhibition and Medicinal Chemistry, v.
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8. DE OLIVEIRA RAMALHO, eresa Raquel et al. Gamma-terpinene modulates
acute inflammatory response in mice. Planta Medica, v. 81, n. 14, p.1248-1254,
9. LEE, Dae-hyo et al. Anti-inflammatory effects of natural flavonoid diosmetin in IL4 and LPS-induced macrophage activation and atopic dermatitis model.
International Immunopharmacology, v. 89, p. 107046, 2020.
10. YIN, Wei et al. Chemical constituents of Citrus medica fruit. Zhong yaocai=
Zhongyaocai= Journal of Chinese Medicinal Materials, v. 38, n. 10, p. 2091-2094,
11. MENICHINI, Federica et al. Chemical composition and bioactivity of Citrus
medica L. cv. Diamante essential oil obtained by hydrodistillation, cold-pressing
and supercritical carbon dioxide extraction. Natural product research, v. 25, n. 8, p.
789-799, 2011
12. VENTURINI, Nicolas et al. Volatile and flavonoid composition of the peel of
Citrus medica L. var. Corsican fruit for quality assessment of its liqueur. Food
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